The Functional Evidence Discussion Forum

The Functional Evidence Forum is a community of practice that focusses on translating experimental data into outcomes for patients with inherited disease. The Forum was co-designed by the community, and is informed through continuing consultation with forum members.

The Functional Evidence Discussion Forum consists of a quarterly online session, with presentations by researchers and clinical curators focused on the use of experimental data in variant classification. The forum has substantial time allocated to discussing the application of the assays presented, and incorporates polls of the audience opinion around the assays presented with consultation results are collated and returned to members.

The Forum is an outcome of the AusMAVE Education project and welcomes all interested professionals to join.

Previous forum sessions -

• May 2025 - Discussing iPSC cells and patient derived assay systems.
• Feb 2025 - Discussing the use of patch clamp assays for cardiac variant classification.
• Oct 2024 - Presenting MaveDB and paving the way forward for improving functional evidence use.

Online Session scoping the discussion forum.

See the information page for details, or join the mailing list to participate.

The Functional Evidence Discussion Forum has a defined Terms of Reference to ensure that members can participate with an understanding of scope and intention. This document establishes the terms of reference for the Functional Evidence Discussion Forum, identifying the scope and preferred practices of the Functional Evidence Discussion Forum community