About
Dr Natalia Ogonowski is a Research Officer in the Computational Neurogenomics Group at QIMR Berghofer. She holds a B.Sc. in Genetics from the National University of Misiones, Argentina, and a Ph.D. in Biomedicine from the University of Buenos Aires, where her research focused on cardiovascular physiology and thyroid dysfunction.
Previously, she conducted postdoctoral training in neurogenetics at the Center for Cognitive Neuroscience (UdeSA, Argentina), and the Latin American Brain Health Institute (BrainLat-UAI, Chile).
Her research explores the genetic and neurobiological basis of complex neurological diseases, focusing on Parkinson’s disease and dementias. She applies advanced genomic and computational techniques to investigate genetic risk factors and multi-omic analyses. With expertise in wet-lab molecular genetics and computational genomics, she is committed to advancing scientific knowledge and making a lasting impact on patients affected by these conditions.
Research Skills
- Statistical Genetics & Bioinformatics
- Epidemiology & Data Science
- Molecular & Cellular Biology
- Functional genomics
- Clinical genetics
Area of Interest
- Functional genomics and high-dimensional omics analysis to understand PD and other neurodegenerative diseases.
- Combining genomics, transcriptomics, and epigenomics data with neuroimaging to enhance the understanding of neurodegeneration.
- Developing cutting-edge diagnostic devices leveraging innovative technologies such as gene editing (e.g., CRISPR-based biosensors), nanotechnology, and single-molecule detection platforms to identify early biomarkers in neurodegenerative diseases.
Awards & Honours
- 2018 Luis Moledo Award – Best Clinical Research in Arterial Hypertension
- 2015 Ma Ángeles Costa Award – Best Basic Research in Arterial Hypertension
Publications
Ogonowski NS, García-Marín LM, Fernando AS, Flores-Ocampo V, Rentería ME. Impact of genetic predisposition to late-onset neurodegenerative diseases on early life outcomes and brain structure, Translational Psychiatry. 2024 Apr 11;14(1):185. doi:10.1038/s41398-024-02898-9
Santiago Diaz-Torres, Natalia Ogonowski, Luis M García-Marín, Luke W Bonham, Claudia Duran-Aniotz, Jennifer S Yokoyama, Miguel E Rentería, Genetic overlap between cortical brain morphometry and frontotemporal dementia risk, Cerebral Cortex, Volume 33, Issue 12, 15 June 2023, Pages 7428–7435, doi:10.1093/cercor/bhad049
Santamaría-García, H., Ogonowsky, N., Baez, S. et al. Neurocognitive patterns across genetic levels in behavioral variant frontotemporal dementia: a multiple single cases study. BMC Neurology 22, 454 (2022). doi:10.1186/s12883-022-02954-1