About
Dr Monica Ng is a staff specialist nephrologist and clinician scientist at Metro North Kidney Health Service where she leads the Research Portfolio and Clinical Trials Unit. Her other appointments include Clinician Scientist in the Cardiac Drug Discovery laboratory at QIMR Berghofer and, Senior Lecturer and Clinical Theme Co-lead of Centre for Cardiovascular Health and Research at University of Queensland.
She completed physician training at Royal Brisbane and Women’s Hospital and Princess Alexandra Hospital in Brisbane. Her PhD studies on the toxicity of prolonged blood product storage were completed concurrently whilst completing medical school and physician training (2013-2019). Since 2019, Dr Ng has channelled her laboratory and clinical research skills to improve information available for patient counselling, evaluate druggable targets for kidney disease and apply current-edge technologies (e.g. spatial transcriptomics, nanoparticle flow cytometry) for biomarker discovery in nephrology. These goals are achieved using a range of methodologies including registry data analysis, data linkage, extracellular vesicle analysis and cell culture, and clinical trial techniques.
Dr Ng contributes expertise to national and international steering committees as: Deputy Chair of the Australian and New Zealand Society of Nephrology Education and Training Committee, Asia-Pacific Co-Chair of the International Society of Extracellular Vesicles’ Genitourinary Special Interest Group and Member of Australasian Kidney Trials Network Chronic Kidney Disease-Glomerular Disease Working Group. In 2026, she was appointed to the American Society of Nephrology Editorial Board.
Research Skills
- Registry data analysis
- Clinical trials
- Extracellular vesicle isolation
- Single extracellular vesicle flow cytometry
- Bulk multi-omics of extracellular vesicles
- Fluorescence and confocal microscopy
Area of Interest
- Kidney fibrosis
- Chronic kidney disease
- Glomerular disease
- Cardiovascular-kidney-metabolic syndrome
- Kidney transplantation
Professional Associations
- International Society of Extracellular Vesicles (ISEV) – Asia-Pacific co-chair of Genitourinary System Extracellular Vesicles Special Interest Group
- American Society of Nephrology (ASN) – Fellow of the American Society of Nephrology (FASN)
- Australia and New Zealand Society of Nephrology (ANZSN) – Deputy Chair of the Education and Training Committee
Funding
- Royal Brisbane and Women’s Hospital Consumers in Research Startup Grant, Co-designing studies to advance diagnostics and therapies for cardiovascular-kidney-metabolic syndrome (CIA, 2026)
- Royal Brisbane and Women’s Hospital SERTA Grant, BOOST-CKD, Better Outcomes via Optimised Sequential Therapy in CKD (CIB, 2026)
- Queensland Health Clinical Research Fellowship, REduce Complications Associated with Nephrological Tests (RECANT) study (CIA, 2024-2026)
- Jacquot Research Establishment Fellowship, Kidney Extracellular Vesicle Atlas – an Initiative to Advance Clinical Translation of Nanoparticle Analytics (CIA, 2025-2026)
- Royal Brisbane and Women’s Hospital SERTA Grant, Simulating Home urine collection and storage under Real world conditions for non-invasive Extracellular vesicle-based tests to reduce hospital admissions (SHRED) study (CIB, 2025-2026)
Research Projects
Current Research Projects
Cardiovascular-Kidney-Metabolic syndrome
Extracellular vesicles as non-invasive diagnostic tests for kidney disease
Immunosuppression after kidney graft failure
Publications
Trachtman H, Kretzler M, Gesualdo L, Cross N, Workeneh B, Kaufeld J, Meijers B, Ye Z, Chen Q, Derebail VK, Ng MSY, Ji Bo, Lobmeyer MT, Retlich S, Licariao Rocha FT, Prasad S, Soleymanlou N. TRPC6 inhibition for the treatment of focal segmental glomerulosclerosis: a randomized, placebo-controlled, phase 2 trial of BI 764198. Lancet. 2026 Feb 7;407(10528):587-598. doi: 10.1016/S0140-6736(25)02255-X.
Brennan RM, Strimatitis B, Tian Y, Adams B, Ellis R, Chandler S, Palamuthusingam D, Ratanjee S, Ranganathan D, Hepburn K, O’Sullivan ED, John G, Doucet B, Healy HG, Kassianos AJ, Ng MSY. Impacts of COVID-19 pandemic on kidney biopsy research, practice and diagnoses: a cross-sectional audit. Medicine. 2025 Nov 7;104(45):e45597. doi: 10.1097/MD.0000000000045597.
Droste M, Puhka M, van Royen ME, Ng MSY, Blijdorp C, Alvarez-Llamas G, Borràs FE, Büscher AK, Bussolati B, Dear JW, Falcón-Pérez JM, Giebel B, Grange C, Hoorn EJ, Leivo J, Lenassi M, Llorente A, Lucien F, Mertens I, Mischak H, Pink D, Tertel T, Tiwari S, Di Vizio D, Yuen PST, Zarovni N, Jenster G, Burger D, Martens-Uzunova ES, Erdbrügger U. Roadblocks of Urinary EV Biomarkers: Moving Toward the Clinic. J Extracell Vesicles. 2025 Jul;14(7):e70120. doi: 10.1002/jev2.70120.